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Presenilin-1 regulates the constitutive turnover of the fibronectin matrix in endothelial cells
BACKGROUND: Presenilin-1 (PS1) is a transmembrane protein first discovered because of its association with familial Alzheimer’s disease. Mice with null mutations in PS1 die shortly after birth exhibiting multiple CNS and non-CNS abnormalities. One of the most prominent features in the brains of PS1−...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556133/ https://www.ncbi.nlm.nih.gov/pubmed/23259730 http://dx.doi.org/10.1186/1471-2091-13-28 |