The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell cycle arrest after DNA damage

The RNA helicase p68 (DDX5) is an established co-activator of the p53 tumour suppressor that itself plays a pivotal role in orchestrating the cellular response to DNA damage. Although several factors influence the biological outcome of p53 activation, the mechanisms governing the choice between cell...

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Detalles Bibliográficos
Autores principales: Nicol, Samantha M., Bray, Susan E., Black, H. Derek, Lorimore, Sally A., Wright, Eric G., Lane, David P., Meek, David W., Coates, Philip J., Fuller-Pace, Frances V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556166/
https://www.ncbi.nlm.nih.gov/pubmed/22986526
http://dx.doi.org/10.1038/onc.2012.426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556166/
https://www.ncbi.nlm.nih.gov/pubmed/22986526
http://dx.doi.org/10.1038/onc.2012.426

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