Cargando…

Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator

BACKGROUND: Currently, the step-wise integration of tet-dependent transactivator and tet-responsive expression unit is considered to be the most promising tool to achieve stable tet-controlled gene expression in cell populations. However, disadvantages of this strategy for integration into primary c...

Descripción completa

Detalles Bibliográficos
Autores principales: Heinz, Niels, Hennig, Katharina, Loew, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556329/
https://www.ncbi.nlm.nih.gov/pubmed/23336718
http://dx.doi.org/10.1186/1472-6750-13-5