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Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator
BACKGROUND: Currently, the step-wise integration of tet-dependent transactivator and tet-responsive expression unit is considered to be the most promising tool to achieve stable tet-controlled gene expression in cell populations. However, disadvantages of this strategy for integration into primary c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556329/ https://www.ncbi.nlm.nih.gov/pubmed/23336718 http://dx.doi.org/10.1186/1472-6750-13-5 |