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Absorption, metabolism and excretion of [(14)C]pomalidomide in humans following oral administration

PURPOSE: To investigate the pharmacokinetics and disposition of [(14)C]pomalidomide following a single oral dose to healthy male subjects. METHODS: Eight subjects were administered a single 2 mg oral suspension of [(14)C]pomalidomide. Blood (plasma), urine and feces were collected. Mass balance of r...

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Detalles Bibliográficos
Autores principales: Hoffmann, Matthew, Kasserra, Claudia, Reyes, Josephine, Schafer, Peter, Kosek, Jolanta, Capone, Lori, Parton, Anastasia, Kim-Kang, Heasook, Surapaneni, Sekhar, Kumar, Gondi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556473/
https://www.ncbi.nlm.nih.gov/pubmed/23203815
http://dx.doi.org/10.1007/s00280-012-2040-6