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Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion
Nature has exploited medium-sized 8- to 11-membered rings in a variety of natural products to address diverse and challenging biological targets. However, due to the limitations of conventional cyclization-based approaches to medium-ring synthesis, these structures remain severely underrepresented i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556477/ https://www.ncbi.nlm.nih.gov/pubmed/23160003 http://dx.doi.org/10.1038/nchembio.1130 |