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Clonal Evolution and Therapeutic Resistance in Solid Tumors

Tumors frequently arise as a result of an acquired genomic instability and the subsequent evolution of neoplastic populations with variable genomes. A barrier to the study of the somatic genetics of human solid tumors in vivo is the presence of admixtures of non-neoplastic cells with normal genomes...

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Detalles Bibliográficos
Autores principales: Barrett, Michael T., Lenkiewicz, Elizabeth, Evers, Lisa, Holley, Tara, Ruiz, Christian, Bubendorf, Lukas, Sekulic, Aleksander, Ramanathan, Ramesh K., Von Hoff, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556559/
https://www.ncbi.nlm.nih.gov/pubmed/23372550
http://dx.doi.org/10.3389/fphar.2013.00002