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The role of tumor suppressor p15Ink4b in the regulation of hematopoietic progenitor cell fate

Epigenetic silencing of the tumor suppressor gene p15Ink4b (CDKN2B) is a frequent event in blood disorders like acute myeloid leukemia and myelodysplastic syndromes. The molecular function of p15Ink4b in hematopoietic differentiation still remains to be elucidated. Our previous study demonstrated th...

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Detalles Bibliográficos
Autores principales: Humeniuk, R, Rosu-Myles, M, Fares, J, Koller, R, Bies, J, Wolff, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556574/
https://www.ncbi.nlm.nih.gov/pubmed/23359317
http://dx.doi.org/10.1038/bcj.2012.44