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Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia

Pediatric leukemia survival rates have improved dramatically over the past decades. However, current treatment protocols are still largely ineffective in cases of relapsed leukemia and are associated with a significant rate of chronic health conditions. Thus, there is a continued need for new therap...

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Detalles Bibliográficos
Autores principales: Brandao, L N, Winges, A, Christoph, S, Sather, S, Migdall-Wilson, J, Schlegel, J, McGranahan, A, Gao, D, Liang, X, DeRyckere, D, Graham, D K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556576/
https://www.ncbi.nlm.nih.gov/pubmed/23353780
http://dx.doi.org/10.1038/bcj.2012.46