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Efficacy of Post Exposure Administration of Doxycycline in a Murine Model of Inhalational Melioidosis

Burkholderia pseudomallei is the causative agent of melioidosis. Treatment of melioidosis is suboptimal and developing improved melioidosis therapies requires animal models. In this report, we exposed male BALB/c mice to various amounts of aerosolized B. pseudomallei 1026b to determine lethality. Af...

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Detalles Bibliográficos
Autores principales: Gelhaus, H. Carl, Anderson, Michael S., Fisher, David A., Flavin, Michael T., Xu, Ze-Qi, Sanford, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556592/
https://www.ncbi.nlm.nih.gov/pubmed/23359492
http://dx.doi.org/10.1038/srep01146