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Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is known how ER stress is implicated in LPS-induced lung inflammation. In this study, effects...

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Detalles Bibliográficos
Autores principales: Kim, Hee Jung, Jeong, Jae Seok, Kim, So Ri, Park, Seung Yong, Chae, Han Jung, Lee, Yong Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556596/
https://www.ncbi.nlm.nih.gov/pubmed/23359618
http://dx.doi.org/10.1038/srep01142