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Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival

BACKGROUND: Glioblastoma multiforme, the most common type of primary brain tumor in adults, is driven by cells with neural stem (NS) cell characteristics. Using derivation methods developed for NS cells, it is possible to expand tumorigenic stem cells continuously in vitro. Although these glioblasto...

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Detalles Bibliográficos
Autores principales: Engström, Pär G, Tommei, Diva, Stricker, Stefan H, Ender, Christine, Pollard, Steven M, Bertone, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556652/
https://www.ncbi.nlm.nih.gov/pubmed/23046790
http://dx.doi.org/10.1186/gm377