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Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH

Large-scale genome-wide SNP association studies have identified an association between variants of CR1, the gene encoding complement component receptor 1, and the sporadic form of Alzheimer's disease. The role of CR1 and the complement system in Alzheimer's disease remains far from clear....

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Detalles Bibliográficos
Autores principales: Killick, R., Hughes, T.R., Morgan, B.P., Lovestone, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556777/
https://www.ncbi.nlm.nih.gov/pubmed/23153828
http://dx.doi.org/10.1016/j.neulet.2012.11.008