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ErbB1 epidermal growth factor receptor is a valid target for reducing the effects of multiple inhibitors of axonal regeneration

Pharmacological inhibitors of epidermal growth factor receptor (ErbB1) attenuate the ability of CNS myelin to inhibit axonal regeneration. However, it has been claimed that such effects are mediated by off-target interactions. We have tested the role of ErbB1 in axonal regeneration by culturing neur...

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Detalles Bibliográficos
Autores principales: Leinster, Veronica H.L., Joy, Mary T., Vuononvirta, Raisa E., Bolsover, Stephen R., Anderson, Patrick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556781/
https://www.ncbi.nlm.nih.gov/pubmed/23022459
http://dx.doi.org/10.1016/j.expneurol.2012.09.007