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ErbB1 epidermal growth factor receptor is a valid target for reducing the effects of multiple inhibitors of axonal regeneration
Pharmacological inhibitors of epidermal growth factor receptor (ErbB1) attenuate the ability of CNS myelin to inhibit axonal regeneration. However, it has been claimed that such effects are mediated by off-target interactions. We have tested the role of ErbB1 in axonal regeneration by culturing neur...
Autores principales: | Leinster, Veronica H.L., Joy, Mary T., Vuononvirta, Raisa E., Bolsover, Stephen R., Anderson, Patrick N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556781/ https://www.ncbi.nlm.nih.gov/pubmed/23022459 http://dx.doi.org/10.1016/j.expneurol.2012.09.007 |
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