Cargando…

Deficiency of α-1-antitrypsin influences systemic iron homeostasis

There is evidence that proteases and antiproteases participate in the iron homeostasis of cells and living systems. We tested the postulate that α-1 antitrypsin (A1AT) polymorphism and the consequent deficiency of this antiprotease in humans are associated with a systemic disruption in iron homeosta...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghio, Andrew J, Soukup, Joleen M, Richards, Judy H, Fischer, Bernard M, Voynow, Judith A, Schmechel, Donald E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556862/
https://www.ncbi.nlm.nih.gov/pubmed/23378755
http://dx.doi.org/10.2147/COPD.S37897