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Deficiency of α-1-antitrypsin influences systemic iron homeostasis
There is evidence that proteases and antiproteases participate in the iron homeostasis of cells and living systems. We tested the postulate that α-1 antitrypsin (A1AT) polymorphism and the consequent deficiency of this antiprotease in humans are associated with a systemic disruption in iron homeosta...
Autores principales: | Ghio, Andrew J, Soukup, Joleen M, Richards, Judy H, Fischer, Bernard M, Voynow, Judith A, Schmechel, Donald E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556862/ https://www.ncbi.nlm.nih.gov/pubmed/23378755 http://dx.doi.org/10.2147/COPD.S37897 |
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