A FOXO3/IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

Antiviral responses must be tightly regulated to rapidly defend against infection while minimizing inflammatory damage. Type 1 interferons (IFN-I) are crucial mediators of antiviral responses(1) and their transcription is regulated by a variety of transcription factors(2); principal amongst these is...

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Detalles Bibliográficos
Autores principales: Litvak, Vladimir, Ratushny, Alexander V., Lampano, Aaron E., Schmitz, Frank, Huang, Albert C., Raman, Ayush, Rust, Alistair G., Bergthaler, Andreas, Aitchison, John D., Aderem, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556990/
https://www.ncbi.nlm.nih.gov/pubmed/22982991
http://dx.doi.org/10.1038/nature11428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556990/
https://www.ncbi.nlm.nih.gov/pubmed/22982991
http://dx.doi.org/10.1038/nature11428

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