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A FOXO3/IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
Antiviral responses must be tightly regulated to rapidly defend against infection while minimizing inflammatory damage. Type 1 interferons (IFN-I) are crucial mediators of antiviral responses(1) and their transcription is regulated by a variety of transcription factors(2); principal amongst these is...
Autores principales: | Litvak, Vladimir, Ratushny, Alexander V., Lampano, Aaron E., Schmitz, Frank, Huang, Albert C., Raman, Ayush, Rust, Alistair G., Bergthaler, Andreas, Aitchison, John D., Aderem, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556990/ https://www.ncbi.nlm.nih.gov/pubmed/22982991 http://dx.doi.org/10.1038/nature11428 |
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