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Role of N-terminal protein formylation in central metabolic processes in Staphylococcus aureus

BACKGROUND: Bacterial protein biosynthesis usually depends on a formylated methionyl start tRNA but Staphylococcus aureus is viable in the absence of Fmt, the tRNA(Met) formyl transferase. fmt mutants exhibit reduced growth rates indicating that the function of certain proteins depends on formylated...

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Detalles Bibliográficos
Autores principales: Mader, Diana, Liebeke, Manuel, Winstel, Volker, Methling, Karen, Leibig, Martina, Götz, Friedrich, Lalk, Michael, Peschel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557171/
https://www.ncbi.nlm.nih.gov/pubmed/23320528
http://dx.doi.org/10.1186/1471-2180-13-7