Pathway choice in DNA double strand break repair: observations of a balancing act

Proper repair of DNA double strand breaks (DSBs) is vital for the preservation of genomic integrity. There are two main pathways that repair DSBs, Homologous recombination (HR) and Non-homologous end-joining (NHEJ). HR is restricted to the S and G2 phases of the cell cycle due to the requirement for...

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Detalles Bibliográficos
Autores principales: Brandsma, Inger, Gent, Dik C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557175/
https://www.ncbi.nlm.nih.gov/pubmed/23181949
http://dx.doi.org/10.1186/2041-9414-3-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557175/
https://www.ncbi.nlm.nih.gov/pubmed/23181949
http://dx.doi.org/10.1186/2041-9414-3-9

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