Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis

BACKGROUND: Leukotrienes are potent inflammatory mediators, which in a number of studies have been found to be associated with ischemic stroke pathology: gene variants affecting leukotriene synthesis, including the FLAP (ALOX5AP) gene, have in human studies shown correlation to stroke incidence, and...

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Detalles Bibliográficos
Autores principales: Ström, Jakob O, Strid, Tobias, Hammarström, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557197/
https://www.ncbi.nlm.nih.gov/pubmed/23194405
http://dx.doi.org/10.1186/1471-2202-13-146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557197/
https://www.ncbi.nlm.nih.gov/pubmed/23194405
http://dx.doi.org/10.1186/1471-2202-13-146

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