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Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Aging is associated chronic inflammation and autoimmunity, and increased levels of leptin. Increased levels of leptin are associated with inflammation and autoimmunity. We have recently reported that leptin activates B cells to induce secretion of proinflammatory and anti-inflammatory cytokines. Rol...

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Detalles Bibliográficos
Autores principales: Gupta, Sudhir, Agrawal, Sudhanshu, Gollapudi, Sastry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557206/
https://www.ncbi.nlm.nih.gov/pubmed/23343052
http://dx.doi.org/10.1186/1742-4933-10-3