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The Brominated Compound Aeroplysinin-1 Inhibits Proliferation and the Expression of Key Pro- Inflammatory Molecules in Human Endothelial and Monocyte Cells

Aeroplysinin-1 is a brominated antibiotic used by some sponges for defense against bacterial pathogen invasion. Aeroplysinin-1 has a wide spectrum of anti-tumoral action and behaves as a potent anti-angiogenic compound for bovine aortic endothelial cells. In this study, we demonstrate anti-angiogeni...

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Detalles Bibliográficos
Autores principales: Martínez-Poveda, Beatriz, García-Vilas, Javier A., Cárdenas, Casimiro, Melgarejo, Esther, Quesada, Ana R., Medina, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557235/
https://www.ncbi.nlm.nih.gov/pubmed/23383109
http://dx.doi.org/10.1371/journal.pone.0055203