FHL2 Silencing Reduces Wnt Signaling and Osteosarcoma Tumorigenesis In Vitro and In Vivo

BACKGROUND: The molecular mechanisms that are involved in the growth and invasiveness of osteosarcoma, an aggressive and invasive primary bone tumor, are not fully understood. The transcriptional co-factor FHL2 (four and a half LIM domains protein 2) acts as an oncoprotein or as a tumor suppressor d...

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Detalles Bibliográficos
Autores principales: Brun, Julia, Dieudonné, François-Xavier, Marty, Caroline, Müller, Judith, Schüle, Roland, Patiño-García, Ana, Lecanda, Fernando, Fromigué, Olivia, Marie, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557236/
https://www.ncbi.nlm.nih.gov/pubmed/23383046
http://dx.doi.org/10.1371/journal.pone.0055034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557236/
https://www.ncbi.nlm.nih.gov/pubmed/23383046
http://dx.doi.org/10.1371/journal.pone.0055034

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