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Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation

Andrographolide (Andro) suppresses proliferation and triggers apoptosis in many types of cancer cells. Taxifolin (Taxi) has been proposed to prevent cancer development similar to other dietary flavonoids. In the present study, the cytotoxic and apoptotic effects of the addition of Andro alone and An...

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Detalles Bibliográficos
Autores principales: Zhang, Zhong Rong, Al Zaharna, Mazen, Wong, Matthew Man-Kin, Chiu, Sung-Kay, Cheung, Hon-Yeung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557238/
https://www.ncbi.nlm.nih.gov/pubmed/23382917
http://dx.doi.org/10.1371/journal.pone.0054577