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Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation
Andrographolide (Andro) suppresses proliferation and triggers apoptosis in many types of cancer cells. Taxifolin (Taxi) has been proposed to prevent cancer development similar to other dietary flavonoids. In the present study, the cytotoxic and apoptotic effects of the addition of Andro alone and An...
Autores principales: | Zhang, Zhong Rong, Al Zaharna, Mazen, Wong, Matthew Man-Kin, Chiu, Sung-Kay, Cheung, Hon-Yeung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557238/ https://www.ncbi.nlm.nih.gov/pubmed/23382917 http://dx.doi.org/10.1371/journal.pone.0054577 |
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