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Dengue Virus Enhances Thrombomodulin and ICAM-1 Expression through the Macrophage Migration Inhibitory Factor Induction of the MAPK and PI3K Signaling Pathways

Dengue virus (DV) infections cause mild dengue fever (DF) or severe life-threatening dengue hemorrhagic fever (DHF). The mechanisms that cause hemorrhage in DV infections remain poorly understood. Thrombomodulin (TM) is a glycoprotein expressed on the surface of vascular endothelial cells that plays...

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Detalles Bibliográficos
Autores principales: Yeh, Trai-Ming, Liu, Shu-Hsiang, Lin, Kao-Chang, Kuo, Chieh, Kuo, Shu-Yun, Huang, Tzuu-Yuan, Yen, Yong-Ren, Wen, Rong-Kun, Chen, Lien-Cheng, Fu, Tsai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557271/
https://www.ncbi.nlm.nih.gov/pubmed/23383040
http://dx.doi.org/10.1371/journal.pone.0055018