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Relationship between LTR Methylation and gag Expression of HIV-1 in Human Spermatozoa and Sperm-Derived Embryos

OBJECTIVE: Studying the methylation status of long terminal repeats (LTR) and its relationship to gag expression of HIV-1 in order to explore regulation mechanism of HIV-1 gene expression in vertical transmission from sperm to embryo. METHODS/PRINCIPAL FINDINGS: Sperm samples were collected from a h...

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Detalles Bibliográficos
Autores principales: Li, FangZheng, Li, LianBing, Zhong, Ying, Xie, QingDong, Huang, JiHua, Kang, XiangJin, Wang, Dian, Xu, Lan, Huang, TianHua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557281/
https://www.ncbi.nlm.nih.gov/pubmed/23382972
http://dx.doi.org/10.1371/journal.pone.0054801