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Convective washout reduces the antidiarrheal efficacy of enterocyte surface–targeted antisecretory drugs
Secretory diarrheas such as cholera are a major cause of morbidity and mortality in developing countries. We previously introduced the concept of antisecretory therapy for diarrhea using chloride channel inhibitors targeting the cystic fibrosis transmembrane conductance regulator channel pore on the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557305/ https://www.ncbi.nlm.nih.gov/pubmed/23359285 http://dx.doi.org/10.1085/jgp.201210885 |