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Voltage-dependent gating of the Cx32*43E1 hemichannel: Conformational changes at the channel entrances

Voltage is an important parameter that regulates the open probability of both intercellular channels (gap junctions) and undocked hemichannels formed by members of the connexin gene family. All connexin channels display two distinct voltage-gating processes, termed loop- or slow-gating and V(j)- or...

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Detalles Bibliográficos
Autores principales: Kwon, Taekyung, Tang, Qingxiu, Bargiello, Thaddeus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557306/
https://www.ncbi.nlm.nih.gov/pubmed/23319727
http://dx.doi.org/10.1085/jgp.201210839