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Ca(2+) oscillations, Ca(2+) sensitization, and contraction activated by protein kinase C in small airway smooth muscle

Protein kinase C (PKC) has been implicated in the regulation of smooth muscle cell (SMC) contraction and may contribute to airway hyperresponsiveness. Here, we combined optical and biochemical analyses of mouse lung slices to determine the effects of PKC activation on Ca(2+) signaling, Ca(2+) sensit...

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Detalles Bibliográficos
Autores principales: Mukherjee, Seema, Trice, Jacquelyn, Shinde, Paurvi, Willis, Ray E., Pressley, Thomas A., Perez-Zoghbi, Jose F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557311/
https://www.ncbi.nlm.nih.gov/pubmed/23359281
http://dx.doi.org/10.1085/jgp.201210876