Mechanism of sodium channel Na(V)1.9 potentiation by G-protein signaling

Tetrodotoxin (TTX)-resistant voltage-gated Na (Na(V)) channels have been implicated in nociception. In particular, Na(V)1.9 contributes to expression of persistent Na current in small diameter, nociceptive sensory neurons in dorsal root ganglia and is required for inflammatory pain sensation. Using...

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Detalles Bibliográficos
Autores principales: Vanoye, Carlos G., Kunic, Jennifer D., Ehring, George R., George, Alfred L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557314/
https://www.ncbi.nlm.nih.gov/pubmed/23359282
http://dx.doi.org/10.1085/jgp.201210919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557314/
https://www.ncbi.nlm.nih.gov/pubmed/23359282
http://dx.doi.org/10.1085/jgp.201210919

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