Cargando…

Mechanism of sodium channel Na(V)1.9 potentiation by G-protein signaling

Tetrodotoxin (TTX)-resistant voltage-gated Na (Na(V)) channels have been implicated in nociception. In particular, Na(V)1.9 contributes to expression of persistent Na current in small diameter, nociceptive sensory neurons in dorsal root ganglia and is required for inflammatory pain sensation. Using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanoye, Carlos G., Kunic, Jennifer D., Ehring, George R., George, Alfred L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557314/ https://www.ncbi.nlm.nih.gov/pubmed/23359282 http://dx.doi.org/10.1085/jgp.201210919

Ejemplares similares

Single-channel Properties of Human Na(V)1.1 and Mechanism of Channel Dysfunction in SCN1A-associated Epilepsy
por: Vanoye, Carlos G., et al.
Publicado: (2006)

Heat-resistant action potentials require TTX-resistant sodium channels Na(V)1.8 and Na(V)1.9
por: Touska, Filip, et al.
Publicado: (2018)

Tramadol as a Voltage-Gated Sodium Channel Blocker of Peripheral Sodium Channels Na(v)1.7 and Na(v)1.5
por: Bok, Chan-Su, et al.
Publicado: (2023)

Scanning mutagenesis of the voltage-gated sodium channel Na(V)1.2 using base editing
por: Pablo, Juan Lorenzo B., et al.
Publicado: (2023)

Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes Na(V)1.9, Na(V)1.7 and Na(V)1.1
por: Touska, Filip, et al.
Publicado: (2017)

Epilepsy-associated SCN2A (Na(V)1.2) Variants Exhibit Diverse and Complex Functional Properties
por: Thompson, Christopher H., et al.
Publicado: (2023)

Reduced Na(v)1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics
por: Pal, Dinesh, et al.
Publicado: (2015)

A central mechanism of analgesia in mice and humans lacking the sodium channel Na(V)1.7
por: MacDonald, Donald Iain, et al.
Publicado: (2021)

Epilepsy-associated SCN2A (Na(V)1.2) variants exhibit diverse and complex functional properties
por: Thompson, Christopher H., et al.
Publicado: (2023)

Voltage-dependent sodium (Na(V)) channels in group IV sensory afferents
por: Ramachandra, Renuka, et al.
Publicado: (2016)

Molecular dissection of multiphase inactivation of the bacterial sodium channel Na(V)Ab
por: Gamal El-Din, Tamer M., et al.
Publicado: (2019)

Editorial: Inherited Arrhythmias of the Cardiac Sodium Channel Na(v)1.5
por: Amarouch, Mohamed-Yassine, et al.
Publicado: (2021)

Na(V)1.6 and Na(V)1.7 channels are major endogenous voltage-gated sodium channels in ND7/23 cells
por: Lee, Jisoo, et al.
Publicado: (2019)

Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome
por: Brewer, Kathryn R., et al.
Publicado: (2020)

Electrophysiological and Pharmacological Analyses of Na(v)1.9 Voltage-Gated Sodium Channel by Establishing a Heterologous Expression System
por: Zhou, Xi, et al.
Publicado: (2017)

Chemometric Models of Differential Amino Acids at the Na(v)α and Na(v)β Interface of Mammalian Sodium Channel Isoforms
por: Villa-Diaz, Fernando, et al.
Publicado: (2020)

Cellular and behavioral effects of altered Na(V)1.2 sodium channel ion permeability in Scn2a(K1422E) mice
por: Echevarria-Cooper, Dennis M, et al.
Publicado: (2022)

Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation
por: Kuenze, Georg, et al.
Publicado: (2020)

µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na(V)1.7
por: McMahon, Kirsten L., et al.
Publicado: (2022)

Sodium channel Na(v)1.8 immunoreactivity in painful human dental pulp
por: Renton, T, et al.
Publicado: (2005)

Sodium channel Na(v)1.6 accumulates at the site of infraorbital nerve injury
por: Henry, Michael A, et al.
Publicado: (2007)

Na(v)1.7 is the predominant sodium channel in rodent olfactory sensory neurons
por: Ahn, Hye-Sook, et al.
Publicado: (2011)

Proton-dependent inhibition of the cardiac sodium channel Na(v)1.5 by ranolazine
por: Sokolov, S., et al.
Publicado: (2013)

Systematic Study of Binding of µ-Conotoxins to the Sodium Channel Na(V)1.4
por: Mahdavi, Somayeh, et al.
Publicado: (2014)

The Voltage-Gated Sodium Channel Na(v)1.8 Is Expressed in Human Sperm
por: Cejudo-Roman, Antonio, et al.
Publicado: (2013)

Mutations in Na(V)1.5 Reveal Calcium-Calmodulin Regulation of Sodium Channel
por: Nof, Eyal, et al.
Publicado: (2019)

The voltage-gated sodium channel Na(v)1.7 associated with endometrial cancer
por: Liu, Junxiu, et al.
Publicado: (2019)

Life Cycle of the Cardiac Voltage-Gated Sodium Channel Na(V)1.5
por: Dong, Caijuan, et al.
Publicado: (2020)

Electrophysiological characterization of schizophrenia-associated variants in NaV1.2 sodium channel
por: Suslova, M., et al.
Publicado: (2022)

The Na(v)1.9 channel regulates colonic motility in mice
por: Copel, Carine, et al.
Publicado: (2013)

Role of Domain 4 in Sodium Channel Slow Inactivation
por: Mitrovic, Nenad, et al.
Publicado: (2000)

Sodium-Vanadium Bronze Na(9)V(14)O(35): An Electrode Material for Na-Ion Batteries
por: Kirsanova, Maria A., et al.
Publicado: (2021)

Disease-linked supertrafficking of a potassium channel
por: Huang, Hui, et al.
Publicado: (2021)

Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations
por: Huang, Hui, et al.
Publicado: (2018)

Changes of Resurgent Na(+) Currents in the Na(v)1.4 Channel Resulting from an SCN4A Mutation Contributing to Sodium Channel Myotonia
por: Huang, Chiung-Wei, et al.
Publicado: (2020)

Ca(2+)-dependent regulation of sodium channels Na(V)1.4 and Na(V)1.5 is controlled by the post-IQ motif
por: Yoder, Jesse B., et al.
Publicado: (2019)

Development of high-affinity nanobodies specific for Na(V)1.4 and Na(V)1.5 voltage-gated sodium channel isoforms
por: Srinivasan, Lakshmi, et al.
Publicado: (2022)

Characterization of the Prokaryotic Sodium Channel Na(v)Sp Pore with a Microfluidic Bilayer Platform
por: Saha, Shimul Chandra, et al.
Publicado: (2015)

Sodium channel Na(V)1.3 is important for enterochromaffin cell excitability and serotonin release
por: Strege, Peter R., et al.
Publicado: (2017)

The functional consequences of sodium channel Na(V)1.8 in human left ventricular hypertrophy
por: Ahmad, Shakil, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_m62egndeersf56fn28bqe5urrc