Cargando…

PAPTi: A Peptide Aptamer Interference Toolkit for Perturbation of Protein-Protein Interaction Networks

Signaling proteins often form dynamic protein-protein interaction (PPI) complexes to achieve multi-functionality. Methods to abrogate a subset of PPI interfaces without depleting the full-length protein will be valuable for structure-function relationship annotations. Here, we describe the use of Pe...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Johannes T. -H., Binari, Richard, Gocha, Tenzin, Dasgupta, Ramanuj, Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557448/
https://www.ncbi.nlm.nih.gov/pubmed/23362456
http://dx.doi.org/10.1038/srep01156