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High Expression of Methylotrophic Yeast-Derived Recombinant Human Erythropoietin in a pH-Controlled Batch System

To accomplish the worldwide demand for recombinant human erythropoietin (rHuEpo) as a therapeutic, application of cost-efficient expression system of methylotrophic yeast Pichia pastoris (P. pastoris) rather than mammalian cells is indispensable. Herein, a report on high levels secreted-expression o...

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Detalles Bibliográficos
Autores principales: Maleki, Ahmad, Roohvand, Farzin, Tajerzadeh, Hosnieh, Khanahmad, Hossein, Nobari, Maryam B., Beiruti, Ahmad, Najafabadi, Abdolhossein Rouholamini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558167/
https://www.ncbi.nlm.nih.gov/pubmed/23407145