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Decreased Semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease of which the pathogenetic mechanisms are not fully understood. Semaphorin3A (Sema3A) has an immune regulatory role. Neuropilin1 (NRP1), the primary receptor for Sema3A, is also a receptor for vascular endothelial growth factor 165 (VEGF(...

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Detalles Bibliográficos
Autores principales: Takagawa, Shu, Nakamura, Fumio, Kumagai, Ken, Nagashima, Yoji, Goshima, Yoshio, Saito, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558329/
https://www.ncbi.nlm.nih.gov/pubmed/23343469
http://dx.doi.org/10.1186/1471-2474-14-40