Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells

BACKGROUND: Cellular FLICE-Inhibitory Protein (long form, c-FLIP(L)) is a critical negative regulator of death receptor-mediated apoptosis. Overexpression of c-FLIP(L) has been reported in many cancer cell lines and is associated with chemoresistance. In contrast, down-regulation of c-FLIP may drive...

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Detalles Bibliográficos
Autores principales: Wang, Qilin, Sun, Wendong, Hao, Xuexi, Li, Tianliang, Su, Ling, Liu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558364/
https://www.ncbi.nlm.nih.gov/pubmed/23256568
http://dx.doi.org/10.1186/1475-2867-12-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558364/
https://www.ncbi.nlm.nih.gov/pubmed/23256568
http://dx.doi.org/10.1186/1475-2867-12-54

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