Cargando…

Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells

BACKGROUND: Cellular FLICE-Inhibitory Protein (long form, c-FLIP(L)) is a critical negative regulator of death receptor-mediated apoptosis. Overexpression of c-FLIP(L) has been reported in many cancer cell lines and is associated with chemoresistance. In contrast, down-regulation of c-FLIP may drive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qilin, Sun, Wendong, Hao, Xuexi, Li, Tianliang, Su, Ling, Liu, Xiangguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558364/ https://www.ncbi.nlm.nih.gov/pubmed/23256568 http://dx.doi.org/10.1186/1475-2867-12-54

Ejemplares similares

The dual functions of α-tubulin acetylation in cellular apoptosis and autophage induced by tanespimycin in lung cancer cells
por: Wang, Qilin, et al.
Publicado: (2020)

EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells
por: Cui, Jing, et al.
Publicado: (2015)

Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis
por: Kim, Dong-Joon, et al.
Publicado: (2008)

Cellular FLICE-inhibitory protein is required for T cell survival and cycling
por: Chau, Hien, et al.
Publicado: (2005)

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein
por: Medema, Jan Paul, et al.
Publicado: (1999)

Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis
por: Nazim, Uddin MD, et al.
Publicado: (2016)

Mouse Lung Fibroblast Resistance to Fas-Mediated Apoptosis Is Dependent on the Baculoviral Inhibitor of Apoptosis Protein 4 and the Cellular FLICE-Inhibitory Protein
por: Predescu, Sanda A., et al.
Publicado: (2017)

Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis
por: Hennino, Ana, et al.
Publicado: (2001)

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Flice-Inhibitory Protein Expression during Macrophage Differentiation Confers Resistance to FAS-Mediated Apoptosis
por: Perlman, Harris, et al.
Publicado: (1999)

Viral FLICE inhibitory protein of Rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation
por: Ritthipichai, Krit, et al.
Publicado: (2012)

Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation
por: Ritthipichai, Krit, et al.
Publicado: (2012)

Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein
por: HOU, YU SEN, et al.
Publicado: (2015)

PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer
por: Chai, Zhengbin, et al.
Publicado: (2019)

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells
por: Huangfu, Jingru, et al.
Publicado: (2021)

Inhibition of Death Receptor Signaling by Flice-Inhibitory Protein as a Mechanism for Immune Escape of Tumors
por: French, Lars E., et al.
Publicado: (1999)

Hsp90: From Cellular to Organismal Proteostasis
por: Somogyvári, Milán, et al.
Publicado: (2022)

Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70
por: Fang, Xiaosheng, et al.
Publicado: (2013)

Down-regulation of IFITM1 and its growth inhibitory role in cervical squamous cell carcinoma
por: Zheng, Weinan, et al.
Publicado: (2017)

A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein
por: Yuan, Ziqiao, et al.
Publicado: (2020)

Mitogen-activated Protein Kinase Kinase Antagonized Fas-associated Death Domain Protein–mediated Apoptosis by Induced FLICE-inhibitory Protein Expression
por: Yeh, Jung-Hua, et al.
Publicado: (1998)

Rocaglamide overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase-8 through cellular FLICE-like-inhibitory protein downregulation
por: LUAN, ZHOU, et al.
Publicado: (2015)

Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage
por: Lee, Seung Wook, et al.
Publicado: (2015)

FLIP (Flice-like inhibitory protein) suppresses cytoplasmic double-stranded-RNA-induced apoptosis and NF-κB and IRF3-mediated signaling
por: Handa, Priya, et al.
Publicado: (2011)

Circumventing HSP90 inhibitors via apoptosis block
por: Fennell, Dean A., et al.
Publicado: (2015)

The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression Factors
por: Djerbi, Mounira, et al.
Publicado: (1999)

Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells
por: Li, Tianliang, et al.
Publicado: (2013)

Altered Thymic Selection by Over-Expressing Cellular FLICE Inhibitory Protein in T Cells Causes Lupus-like Syndrome in BALB/c but not C57BL/6 Strain
por: Qiao, Guilin, et al.
Publicado: (2009)

Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
por: MORI, MASAKI, et al.
Publicado: (2014)

Down regulation of G protein-coupled receptor 137 expression inhibits proliferation and promotes apoptosis in leukemia cells
por: Men, Li-Jie, et al.
Publicado: (2018)

Hysterectomy for benign conditions: Complications relative to surgical approach and other variables that lead to post-operative readmission within 90 days of surgery
por: Lonky, Neal M, et al.
Publicado: (2017)

Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc
por: Luo, Haitao, et al.
Publicado: (2010)

Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells
por: Naseri, Mohammad Hassan, et al.
Publicado: (2015)

The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma
por: Wang, Ben, et al.
Publicado: (2021)

Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration
por: Yaqinuddin, Ahmed, et al.
Publicado: (2008)

E1B 19K Inhibits Fas-mediated Apoptosis through FADD-dependent Sequestration of FLICE
por: Perez, Denise, et al.
Publicado: (1998)

Inhibition of the AKT pathway in cholangiocarcinoma by MK2206 reduces cellular viability via induction of apoptosis
por: Wilson, Jacob M, et al.
Publicado: (2015)

Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis
por: Vindrieux, David, et al.
Publicado: (2011)

Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells
por: Zhou, Chao, et al.
Publicado: (2018)

Down-regulation of cylindromatosis protein phosphorylation by BTK inhibitor promotes apoptosis of non-GCB-diffuse large B-cell lymphoma
por: Xu, Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jmb8os1f451banf7fv7nsqte1b