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Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging
BACKGROUND: Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functions as a major player in this response as it activates the transcription of gene...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558376/ https://www.ncbi.nlm.nih.gov/pubmed/23116063 http://dx.doi.org/10.1186/1471-213X-12-32 |