Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231

BACKGROUND: Glibenclamide (Gli) binds to the sulphonylurea receptor (SUR) that is a regulatory subunit of ATP-sensitive potassium channels (K(ATP) channels). Binding of Gli to SUR produces the closure of K(ATP) channels and the inhibition of their activity. This drug is widely used for treatment of...

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Detalles Bibliográficos
Autores principales: Núñez, Mariel, Medina, Vanina, Cricco, Graciela, Croci, Máximo, Cocca, Claudia, Rivera, Elena, Bergoc, Rosa, Martín, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558386/
https://www.ncbi.nlm.nih.gov/pubmed/23311706
http://dx.doi.org/10.1186/2050-6511-14-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558386/
https://www.ncbi.nlm.nih.gov/pubmed/23311706
http://dx.doi.org/10.1186/2050-6511-14-6

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