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P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines

BACKGROUND: Mantle cell lymphoma (MCL) is a well-defined aggressive lymphoid neoplasm characterized by proliferation of mature B-lymphocytes that have a remarkable tendency to disseminate. This tumor is considered as one of the most aggressive lymphoid neoplasms with poor responses to conventional c...

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Detalles Bibliográficos
Autores principales: Shirsath, Nitesh P, Manohar, Sonal M, Joshi, Kalpana S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558400/
https://www.ncbi.nlm.nih.gov/pubmed/23075291
http://dx.doi.org/10.1186/1476-4598-11-77