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Peripheral Blood Monocyte Sirt1 Expression Is Reduced in Patients with Coronary Artery Disease

BACKGROUND: Inflammation plays a key role in atherosclerosis. Sirt1 regulates transcription factors involved in inflammatory processes and blunts atherosclerosis in mice. However, its role in humans remains to be defined. This study was therefore designed to investigate the role of Sirt1 in the deve...

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Detalles Bibliográficos
Autores principales: Breitenstein, Alexander, Wyss, Christophe A., Spescha, Remo D., Franzeck, Fabian C., Hof, Danielle, Riwanto, Meliana, Hasun, Matthias, Akhmedov, Alexander, von Eckardstein, Arnold, Maier, Willibald, Landmesser, Ulf, Lüscher, Thomas F., Camici, Giovanni G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558418/
https://www.ncbi.nlm.nih.gov/pubmed/23382833
http://dx.doi.org/10.1371/journal.pone.0053106