Modification of Hemodynamic and Immune Responses to Exposure with a Weak Antigen by the Expression of a Hypomorphic BMPR2 Gene

BACKGROUND: Hypomorphic mutations in the bone morphogenic protein receptor (BMPR2) confer a much greater risk for developing pulmonary arterial hypertension (PAH). However, not all carriers of a mutation in the BMPR2 gene suffer from PAH. We have previously shown that prolonged T helper 2 (Th2) resp...

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Detalles Bibliográficos
Autores principales: Park, Sung-Hyun, Chen, Wen-Chi, Hoffman, Carol, Marsh, Leigh M., West, James, Grunig, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558423/
https://www.ncbi.nlm.nih.gov/pubmed/23383100
http://dx.doi.org/10.1371/journal.pone.0055180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558423/
https://www.ncbi.nlm.nih.gov/pubmed/23383100
http://dx.doi.org/10.1371/journal.pone.0055180

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