Localized DNA Demethylation at Recombination Intermediates during Immunoglobulin Heavy Chain Gene Assembly

Multiple epigenetic marks have been proposed to contribute to the regulation of antigen receptor gene assembly via V(D)J recombination. Here we provide a comprehensive view of DNA methylation at the immunoglobulin heavy chain (IgH) gene locus prior to and during V(D)J recombination. DNA methylation...

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Detalles Bibliográficos
Autores principales: Selimyan, Roza, Gerstein, Rachel M., Ivanova, Irina, Precht, Patricia, Subrahmanyam, Ramesh, Perlot, Thomas, Alt, Frederick W., Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558432/
https://www.ncbi.nlm.nih.gov/pubmed/23382652
http://dx.doi.org/10.1371/journal.pbio.1001475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558432/
https://www.ncbi.nlm.nih.gov/pubmed/23382652
http://dx.doi.org/10.1371/journal.pbio.1001475

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