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Dynamic changes in the secondary structure of ECE-1 and XCE account for their different substrate specificities
BACKGROUND: X-converting enzyme (XCE) involved in nervous control of respiration, is a member of the M13 family of zinc peptidases, for which no natural substrate has been identified yet. In contrast, it’s well characterized homologue endothelin-converting enzyme-1 (ECE-1) showed broad substrate spe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558449/ https://www.ncbi.nlm.nih.gov/pubmed/23113990 http://dx.doi.org/10.1186/1471-2105-13-285 |