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Dynamic changes in the secondary structure of ECE-1 and XCE account for their different substrate specificities

BACKGROUND: X-converting enzyme (XCE) involved in nervous control of respiration, is a member of the M13 family of zinc peptidases, for which no natural substrate has been identified yet. In contrast, it’s well characterized homologue endothelin-converting enzyme-1 (ECE-1) showed broad substrate spe...

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Detalles Bibliográficos
Autores principales:	Ul-Haq, Zaheer, Iqbal, Sadaf, Moin, Syed Tarique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558449/ https://www.ncbi.nlm.nih.gov/pubmed/23113990 http://dx.doi.org/10.1186/1471-2105-13-285

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