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A novel algorithm for simultaneous SNP selection in high-dimensional genome-wide association studies

BACKGROUND: Identification of causal SNPs in most genome wide association studies relies on approaches that consider each SNP individually. However, there is a strong correlation structure among SNPs that needs to be taken into account. Hence, increasingly modern computationally expensive regression...

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Detalles Bibliográficos
Autores principales: Zuber, Verena, Duarte Silva, A Pedro, Strimmer, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558454/
https://www.ncbi.nlm.nih.gov/pubmed/23113980
http://dx.doi.org/10.1186/1471-2105-13-284