Contrasting Properties of α7-Selective Orthosteric and Allosteric Agonists Examined on Native Nicotinic Acetylcholine Receptors

Subtype-selective ligands are important tools for the pharmacological characterisation of neurotransmitter receptors. This is particularly the case for nicotinic acetylcholine receptors (nAChRs), given the heterogeneity of their subunit composition. In addition to agonists and antagonists that inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Gill, JasKiran K., Chatzidaki, Anna, Ursu, Daniel, Sher, Emanuele, Millar, Neil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558472/
https://www.ncbi.nlm.nih.gov/pubmed/23383051
http://dx.doi.org/10.1371/journal.pone.0055047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558472/
https://www.ncbi.nlm.nih.gov/pubmed/23383051
http://dx.doi.org/10.1371/journal.pone.0055047

Ejemplares similares