Phenytoin Inhibits the Persistent Sodium Current in Neocortical Neurons by Modifying Its Inactivation Properties

The persistent Na(+) current (I(NaP)) is important for neuronal functions and can play a role in several pathologies, although it is small compared to the transient Na(+) current (I(NaT)). Notably, I(NaP) is not a real persistent current because it undergoes inactivation with kinetics in the order o...

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Detalles Bibliográficos
Autores principales: Colombo, Elisa, Franceschetti, Silvana, Avanzini, Giuliano, Mantegazza, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558486/
https://www.ncbi.nlm.nih.gov/pubmed/23383157
http://dx.doi.org/10.1371/journal.pone.0055329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558486/
https://www.ncbi.nlm.nih.gov/pubmed/23383157
http://dx.doi.org/10.1371/journal.pone.0055329

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